- Developed and optimized Curcuma longa L. extract formulations using hydrophobic deep eutectic solvent (HDES)-based microemulsions to enhance gastrointestinal cell protection and skin permeation of active compounds.
- Created microemulsions by combining HDESs (menthol and fatty acids such as acetic acid, lactic acid, and oleic acid) with surfactants (Cremophor RH and Labrasol) to improve stability and effectiveness of the extract.
- Extracted and concentrated Curcuma longa L. using ethanol with an evaporator, followed by vacuum oven drying to obtain purified curcumin for incorporation into the developed microemulsions.
- Conducted comprehensive analytical studies including UV-VIS spectrophotometer, Rheometer, and Zeta potential analysis to evaluate microemulsion properties.
- Assessed stability of curcumin and its derivatives (Demethoxycurcumin, Bisdemethoxycurcumin, and Ar-Turmerone) using High Performance Liquid Chromatography (HPLC), optimizing formulations for long-term efficacy.
- Performed skin permeation tests using Franz Diffusion Cell, comparing HDES-based with MCT-based microemulsions, and analyzed results with HPLC to determine optimal formulation ratios.
- Developed and tested microemulsion formulations for cosmetic products such as facial creams, serums, and clay masks, ensuring high efficacy and stability through dissolution and stability testing, including drug dissolution testing using a Dissolution Tester.